50 ml EVOMEC / Ivomec PLUS Ivermectin 1% Clorsulon 10% heartworm , deworming Cattle Sheep Goats - FREE SHIPPING

Regular price €43,00

EVOMEC PLUS

  • Active substances: Ivermectin, Clorsulon
  • Injectable solution to prevent and treat the infestations with gastrointestinal and pulmonary nematodes, trematodes, scabies, entomosis, ectoparasites
  • Target species: cattle, sheep, goats
  • Administration: subcutaneous
  • Package: 10 ml, 20 ml, 50 ml, 100 ml, 250 ml, 500 ml

 

COMPOSITION

1 ml contains:

Ivermectin………………………………………… 10 mg

Clorsulon………..……………………………..…… 100 mg

Excipient: Glycerol formal, Propylene glycol.

 

PHARMACOTHERAPEUTIC ACTION

Ivermectin is an antiparasitic substance from macrocyclic lactones class, isolated from the product obtained by the fermentation of an actinomycete named Streptomyces avermitilis. It acts by increasing cell membrane permeability to chloride ions with the hyperpolarisation of the nerve or muscle cells, causing paralysis and death of the parasite; it also causes the secretion of gamma aminobutyric acid in the parasite’s nerve synapses, thus leading to interruption of nerve impulses. Clorsulon (benzenesulfonamide) acts against Fasciola spp. (in both immature and mature form), by inhibiting the enzymes involved in the glicolitic cycle (3-phosphoglycerate kinase and phosphoglycero mutase). It is rapidly absorbed in the blood circulation, the efficient plasmatic concentration being reached in about 8 hours after administration.

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TARGET SPECIES

Cattle. Sheep . Goats

 

INDICATIONS

In cattle for the treatment of infestations with:

Gastrointestinal nematodes (adults, L3, L4, inhibitor stages):

Ostertagia spp.

Bunostomum spp.

Haemonchus spp.

Toxocara spp.

Trichostrongylus spp.

Trichocephalus spp.

Cooperia spp.

Oesophagostomum spp.

-  Nematodirus spp.

-  Chabertia spp.

-  Strongyloides spp.

Lung nematodes:

Dictyocaulus spp.

Trematodes (adult and immature):

Fasciola hepatica

Fasciola gigantica

Scabies:

Sarcoptes scabie var bovis

Choroptes bovis

Psoroptes bovis

Entomosis:

Hypoderma bovis (larval stage)

Hypoderma lineatum (larval stage)

Ectoparasites:

Linognatus vituli

Haematopinus eurystemus

Damalinia bovis

- Ticks

 

POSOLOGY, ROUTE AND METHOD OF ADMINISTRATION

It must be administrated strictly subcutaneously in cattle at a dose of 1 ml per 50 kg bodyweight (respectively 0.2 mg ivermectin and 2 mg clorsulon per 1 kg body weight).

As a general rule, the treatment is applied twice a year (in spring and autumn) in unique dose, and in case of scabies the treatment at every 10 – 14 days.

In case of reinfestation ask a veterinarian for advice regarding the frequency of administrating the product and about the necessity to repeat the treatment.

 

CONTRAINDICATIONS, PRECAUTIONS AND ADVERSE REACTIONS

Do not administer intramuscularly or intravenously. Do not administrate the product in case of hypersensitivity to the active substance or to any other excipient. There is no authorization to use the product in lactation animals that produce milk for human consumption. Some transitory edemas might appear in the inoculation spot. In case of overdose (10 – 15 x therapeutic dose) on the inflammation spot edema, tisular fibrosis and necrosis might appear. Do not mix the product in the same syringe with other injectable solutions, in order to avoid precipitation.

 

WITHDRAWL TIME

Meat and organs: 66 days.

Not authorized for use in lactating animals producing milk for human consumption.

 

STORAGE CONDITIONS

At temperatures below 25°C, away from direct sunlight  and freezing. Store in the original container.

 

PACKAGE

Amber glass vials with foreseen with rubber plug and metallic cover with 10 ml, 20 ml, 50 ml, 100 ml, 200 ml, 250 ml, 500 ml solution.

 

MANUFACTURER: S.C. PASTEUR – FILIPEŞTI BRANCH